Arizona Cardinals (4-8) will host the New England Patriots who will begin a two-game road trip in Week 14 as they travel to the Copper State for an inter-conference matchup.

The Hopes for the Cardinals are slowly facing, as they lost four of their last five games. while the Patriots, are also in a tough position even with a 6-6 record. They are at the bottom of the AFC East where the Buffalo Bills led with a 9-3 standing.

Even though the two teams are from different conferences and thus relatively unfamiliar, there is some history between them: two years ago, in 2020, the Patriots were victorious in their last meeting against Arizona, winning 20-17 on a last-second field goal.

Who will prevail at State Farm Stadium?

Patriots vs. Cardinals Odds/Game Lines

Odds from DraftKingsSpreadTotalMoneyline
NE Patriots– 2.5 (-105)Over 44.5 (-110)-130
ARI Cardinals+ 2.5 (-115)Under 44.5 (-110)+110
First Score Method 3-WayTD -170FG +125Safety +2800
Odds from FanDuelSpreadTotalMoneyline
Patriots– 1.5 (-108)Over 44 (-110)-130
Cardinals+ 1.5 (-112)Under 4 (-110)+110
First Drive Result
PuntOffensive TDField Goal AttemptAny Other

More NFL betting options are available through retail and mobile sportsbooks. NFL odds may change depending on the updates before and during the match.

Patriots at Cardinals Week 14 Preview

Bill Belichick’s defensive philosophy has always had the unifying theme of not allowing the opposing team’s standout performers to have a major impact in any given contest. This weekend, however, he and his Patriots face a rather tough task as they take on DeAndre Hopkins, one of the NFL’s most explosive wide receivers.

“He’s got tremendous ball skills,” Belichick stated.

“He catches everything, has great hands, and he’s long, so he’s never covered. Even if he’s covered, there’s a place where the ball can be that he can get it and still make the catch. Great coordination on the sidelines.

Despite sitting out six games due to suspension earlier in the season, Hopkins continues to be the Cardinals’ go-to option in the passing game and is currently first in both receptions (49) and receiving yards (574). Nullifying his effectiveness through technique or double teams will be key for New England this coming Sunday.

While the Cardinals will play at home, it doesn’t necessarily mean it increases their chances of winning. In addition, stunning the Patriots will take more than just a one-man show from Hopkins. According to DraftKings sportsbook, they lost ten out of their last 11 games at State Farm, including their recent three-game losing skid.