The Cardinals find themselves on the road in Week 15 as they head to Empower Field at Mile High Stadium to take on the Denver Broncos. The Cardinals are struggling this season with a 4-9 record and their woes increased when QB Kyler Murray suffered what appears to be a season-ending ACL injury after just 3 snaps during their week 14 match against New England Patriots. Coach Kliff Kingsbury will look to QB Colt McCoy to carry the team against Denver’s defense.

Meanwhile, Denver is also fighting a losing battle this season, with a record of 3-10 and losing five consecutive games before their matchup against the Chiefs in Week 14. They were able to cover as 8.5-point underdogs but concern remains around QB Russell Wilson who suffered a concussion during the game, leading many to question his availability for Sunday’s game versus the Cardinals.

With two teams approaching soon-to-be close seasons, all eyes will be following these teams come kickoff at 4:05 p.m. ET (FOX).

Cardinals vs. Broncos Odds/Game Lines

Odds from DraftKingsSpreadTotalMoneyline
ARI Cardinals+3 (-115)Over 36 (-110)+130
DEN Broncos+3 (-105)Under 36 (-110)-150
Odds from FanDuelSpreadTotalMoneyline
ARI Cardinals+2.5 (-104)Over 36.5 (-110)+120
DEN Broncos-2.5 (-118)Under 36.5 (-110)-142

More NFL betting options are available through retail locations and AZ sportsbooks. NFL odds may change depending on the updates before and during the match.

Cardinals at Broncos Preview

The Denver Broncos and Arizona Cardinals will meet for only the 12th time ever in the regular season when they face off against each other this week. Their last meeting took place back in 2018 and resulted in a 45-10 win for the Broncos. The all-time series is firmly in Denver’s favor, who have won 9 of the games and tied 1; the only losing game for them was back in 2010.

The Arizona Cardinals have announced a rather unexpected roster move in the wake of their 27-13 loss to the New England Patriots. On Tuesday, they released cornerback Trayvon Mullen despite his season-high 42 defensive snaps at the game.

Although Mullen logged 120 total snaps over eight games this season, recording 13 tackles, one pass breakup, one quarterback hit, and a forced fumble in that period, his overall performance apparently failed to meet the team’s expectations.

Cardinals vs Broncos: Injury Updates

The Arizona Cardinals will start Sunday’s game in Denver without one of their key defensive pieces, as head coach Kliff Kingsbury announced on Tuesday that defensive lineman Zach Allen has been ruled out with a hand injury. Allen sustained the injury during the third quarter of Monday’s 27-13 loss to the New England Patriots.

Moreover, Kyler Murray’s MRI on Monday confirmed that he tore his ACL during the last match and he will be out for the rest of the season.

On a slightly brighter note for Arizona’s defense, Kingsbury stated that cornerback Marco Wilson appears to be ready to take the field after picking up a stinger on Monday evening.

“He looks like he’ll be OK.”.

Other Cardinals who are questionable for Week 15 include Rondale Moore, Byron Murphy Jr.. and Rashaad Coward.

With several players sidelined due to injuries, it could prove challenging for the Cardinals’ defense to stiffen up against an energized Broncos offense this weekend.

On the other hand, the Broncos placed Mike Boone (ankle) on injured reserve on Tuesday while QB Russel Wilson is also questionable for Week 15 after head coach Nathaniel Hackett confirmed that he is in concussion protocol.

 “We’ll go through the step-by-step process and do it the right way,” Coach Hackett said.

Other Denver players who are questionable include Courtland Sutton, Eyioma Uwazurike, Dalton Rinser, Andrew Beck, and Dakota Allen.